| Date | Location | Result | |
| 11-17-05 | Martin, Tenn. | Tennessee-Martin 49, Murray State 20 | Box score |
| 11-12-05 | Murray, Ky. | Murray State 42, Austin Peay 6 | Box score |
| 11-05-05 | Murray, Ky. | Eastern Kentucky 43, Murray State 7 | Box score |
| 10-29-05 | Cape Girardeau, Mo. | Southeast Missouri 52, Murray State 21 | Box score |
| 10-22-05 | Murray, Ky. | Eastern Illinois 35, Murray State 28 | Box score |
| 10-15-05 | Birmingham, Ala. | Samford 27, Murray State 23 | Box score |
| 10-08-05 | Murray, Ky. | Jacksonville State 28, Murray State 23 | Box score |
| 10-01-05 | Cookeville, Tenn. | Tennessee Tech 42, Murray State 21 | Box score |
| 09-24-05 | Normal, Ill. | Illinois State 42, Murray State 0 | Box score |
| 09-17-05 | Murray, Ky. | Murray State 27, Indiana State 15 | Box score |
| 09-03-05 | Starkville, Miss. | Mississippi State 38, Murray State 6 | Box score |