| Date | Location | Result | |
| 11-11-00 | Murray, Ky. | Murray State Univ. 62, Tennessee State 40 | Box score |
| 11-04-00 | Richmond, Ky. | Murray State Univ. 24, Eastern Kentucky 22 | Box score |
| 10-28-00 | Murray, Ky. | Tennessee Tech 36, Murray State Univ. 21 | Box score |
| 10-21-00 | Cape Girardeau, Mo. | Murray State Univ. 38, Southeast Missouri 28 | Box score |
| 10-14-00 | Charleston, Ill. | Eastern Illinois 48, Murray State Univ. 7 | Box score |
| 10-07-00 | Martin, Tenn. | Murray State Univ. 48, Tennessee-Martin 3 | Box score |
| 09-30-00 | Murray, Ky. | Western Kentucky 48, Murray State Univ. 38 | Box score |
| 09-23-00 | Murray, Ky. | Murray State Univ. 41, Indiana State 24 | Box score |
| 09-16-00 | Murfreesboro, Tenn. | Middle Tennessee 44, Murray State Univ. 28 | Box score |
| 09-07-00 | Birmingham, Ala. | Samford University 19, Murray State Univ. 17 | Box score |
| 09-31-00 | Murray, Ky. | Murray State Univ. 42, Southern Illinois 20 | Box score |